Simultaneous de novo calling and phasing of genetic variants at chromosome-scale using NanoStrand-seq
Abstract The successful accomplishment of the natio glide on eyeshadow stick first telomere-to-telomere human genome assembly, T2T-CHM13, marked a milestone in achieving completeness of the human reference genome.The upcoming era of genome study will focus on fully phased diploid genome assembly, with an emphasis on genetic differences between indi